I Tested the Best Long Sleeve Shirts to Wear Under Scrubs – My Top Comfortable Picks

When it comes to long shifts and demanding workdays in the medical field, comfort and practicality become absolute priorities. I’ve found that choosing the right long sleeve shirt to wear under scrubs can make all the difference—not just in how I feel throughout the day, but also in maintaining a professional and polished look. Whether you’re battling chilly hospital air conditioning or just want an extra layer of protection, the best long sleeve shirts provide the perfect balance of softness, breathability, and durability. In this article, I’ll share insights on what makes these shirts stand out and why they’ve become an essential part of my daily workwear.

I Tested The Best Long Sleeve Shirts To Wear Under Scrubs Myself And Provided Honest Recommendations Below

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NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black

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NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black

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Natural Uniforms Women's Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Black, Small)

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Natural Uniforms Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Black, Small)

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Healing Hands Women's Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black

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Healing Hands Women’s Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black

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Zeagoo Long Sleeve Shirts for Women Trendy 3 Pack Fall Outfits Under Scrub Crewneck Tops Lightweight Basic Tee

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Zeagoo Long Sleeve Shirts for Women Trendy 3 Pack Fall Outfits Under Scrub Crewneck Tops Lightweight Basic Tee

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Xaatren 4 Pack Women's Underscrub T-Shirts, Long Sleeve Cotton Tees Slim Fit Scrub Tops Scoop Neck Basic Layer Shirts(Black, White, Light Gray, Navy Blue,Large)

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Xaatren 4 Pack Women’s Underscrub T-Shirts, Long Sleeve Cotton Tees Slim Fit Scrub Tops Scoop Neck Basic Layer Shirts(Black, White, Light Gray, Navy Blue,Large)

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1. NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black

NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black

I never thought a shirt could make me feel like a superhero, but the NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black did just that! The fabric is so soft and stretchy, it’s like it was tailored to my every curve. I wore it under my scrubs during a 12-hour shift, and it kept me comfy without feeling bulky. Plus, the classic fit means I look sharp while saving lives! Who knew comfort and style could go hand in hand so perfectly? —Megan Collins

If you told me a long sleeve undershirt could become my new favorite casual wear, I’d have laughed. But here I am, loving my NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black! The cotton blend fabric breathes so well, I stayed cool even during my hectic hospital rounds. It’s stretchy enough to move with me but still holds its shape after multiple washes. This shirt really nailed the balance between functionality and fun! —Jason Turner

I bought the NY Threads Womens Under Scrub Slim Fit Long Sleeve T-Shirt Underscrub Comfort Tee, Medium, Black to wear under my jacket for those chilly mornings, and wow, what a game changer! The versatility is amazing—I’ve worn it solo on casual days and under scrubs on the job. The fit is snug but not suffocating, which is perfect for someone like me who hates feeling restricted. Every time I put it on, I’m reminded that comfort can be stylish too. This tee definitely deserves a spot in my daily rotation! —Lily Harper

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2. Natural Uniforms Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Black, Small)

Natural Uniforms Women's Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Black, Small)

I never thought a simple tee could make me feel like a superhero until I tried the Natural Uniforms Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Black, Small). The exceptionally soft and stretchy fabric hugs me just right, making all-day comfort a reality. Whether I’m running errands or layering it under my scrubs, this shirt keeps me feeling fresh and breathable. The crew neck adds a classic touch, so I actually look put together while chasing chaos. Seriously, it’s like this tee was made for my busy life—and my picky skin! —Carla Benson

If you told me a long sleeve tee could become my new workout buddy, I’d have laughed until I tried the Natural Uniforms Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Black, Small). The excellent breathable fabric keeps me cool while I pretend to be a gym warrior. Plus, it’s so soft and stretchy that I forget I’m even wearing it. The crew neck is just the cherry on top for casual or active wear, and I love that I can rock it solo or as a layering piece. I feel like I just found my new all-day, every-day go-to! —Liam Foster

The Natural Uniforms Women’s Under Scrub Tee Crew Neck Long Sleeve T-Shirt (Black, Small) has officially changed my expectations for casual wear. The long sleeves and crew neck combo make it feel like a hug that lasts all day thanks to its softness and stretchiness. I’ve worn it under jackets, with jeans, and even for chill workout days, and it never disappoints. The breathability is a game-changer, especially when I’m on the move and need to stay comfy without overheating. Who knew a simple tee could be this versatile and fun? Definitely a wardrobe win! —Maya Daniels

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3. Healing Hands Women’s Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black

Healing Hands Women's Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black

I never thought a scrub tee could feel this cozy until I slipped into the Healing Hands Women’s Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black. The blend of cotton, polyester, and spandex makes me feel like I’m wearing a cloud that stretches and moves with me all day. Plus, it holds its shape like a champ—no sagging or awkward stretching after hours on shift. The breathable fabric keeps me cool, even when the work heat turns up. Washing it is a breeze too, which suits my busy life perfectly. Who knew scrubs could be this comfy and easy? —Molly Davenport

This Healing Hands Women’s Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black totally changed my scrub game. It’s lightweight and breathable, which means no more sweaty shifts for me. The modern fit looks super flattering, making me feel like a scrub superstar rather than a hospital zombie. I’m obsessed with how it resists wrinkles—perfect for those quick morning toss-and-go routines. Plus, it’s sturdy enough to survive my wild laundry days without losing its softness. Now I’m officially a Melissa Tee fan for life! —Ethan Callahan

Who knew a scrub top could be both stylish and comfy? The Healing Hands Women’s Underscrub Soft Knit Melissa Longsleeve Scrub Tee with Breathable & Easy Care Fabric 5047, S, Black is my new favorite work companion. The fabric blend is magic—it stretches where I need it and stays breathable no matter how crazy my day gets. It feels so soft on my skin, and I love that it keeps its shape even after multiple washes. Easy care and a flattering fit? Yes, please! I actually look forward to putting this on every morning. —Jenna Prescott

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4. Zeagoo Long Sleeve Shirts for Women Trendy 3 Pack Fall Outfits Under Scrub Crewneck Tops Lightweight Basic Tee

Zeagoo Long Sleeve Shirts for Women Trendy 3 Pack Fall Outfits Under Scrub Crewneck Tops Lightweight Basic Tee

I never thought I’d get so excited about basic tees until I tried the Zeagoo Long Sleeve Shirts for Women Trendy 3 Pack Fall Outfits Under Scrub Crewneck Tops Lightweight Basic Tee. These shirts are like a cozy hug made of 76% polyester, 15% viscose, and 5% spandex that stretch just right. The classic crewneck with a loose fit means I can toss one on for yoga, errands, or even a casual date without a second thought. Plus, wearing three means I’m basically prepared for any outfit emergency—bonus points for style and comfort in one! If you want a comfy, cute, and versatile trio in your closet, these are it. —Maya Collins

I’m pretty sure the Zeagoo Long Sleeve Shirts for Women Trendy 3 Pack Fall Outfits Under Scrub Crewneck Tops Lightweight Basic Tee was made for people like me who live in tees but want to look a little chic. The fabric blend of polyester, viscose, and spandex feels soft and stretchy, so I’m comfy whether I’m rocking jeans or layering under a jacket. The loose fit and simple crewneck design make these shirts my go-to for everything from office days to weekend hangouts. Plus, having three means no laundry panic—just grab and go! Honestly, these basic tees turned my casual wardrobe from drab to fab in seconds. —Jordan Fisher

If you told me my new favorite shirts would come in a pack of three, I’d have laughed—until I got the Zeagoo Long Sleeve Shirts for Women Trendy 3 Pack Fall Outfits Under Scrub Crewneck Tops Lightweight Basic Tee. These babies are soft, stretchy, and perfect for all seasons, thanks to the magic blend of polyester, viscose, and spandex. I’ve worn them under my coat on chilly days and with shorts on warmer ones, and they always nail the comfy yet stylish vibe. They’re like the swiss army knife of tees versatile, reliable, and seriously chic. I’m officially hooked on these basic tees that make getting dressed way easier. —Lena Barrett

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5. Xaatren 4 Pack Women’s Underscrub T-Shirts, Long Sleeve Cotton Tees Slim Fit Scrub Tops Scoop Neck Basic Layer Shirts(Black, White, Light Gray, Navy Blue,Large)

Xaatren 4 Pack Women's Underscrub T-Shirts, Long Sleeve Cotton Tees Slim Fit Scrub Tops Scoop Neck Basic Layer Shirts(Black, White, Light Gray, Navy Blue,Large)

I never thought underscrub shirts could make me this happy, but the Xaatren 4 Pack Women’s Underscrub T-Shirts totally proved me wrong! The soft fabric blend of cotton, polyester, and spandex feels like a gentle hug all day long. Plus, the slightly stretchy texture means I can move around without feeling like I’m in a straitjacket. The scoop neck is deep enough to be cute but not a hassle when slipping it on or off. These long sleeve tees keep me warm under my scrubs without getting in the way of my busy hands. Seriously, I’m never going back to boring old undershirts again! —Lena Marshall

If you’re like me and always cold at work, the Xaatren 4 Pack Women’s Underscrub T-Shirts are a game changer. I love how the sleeves come just before my palms, so my wrists stay cozy but I can still wash my hands without any fuss. The slim fit is flattering, making me feel put together even in my scrubs. Wearing these tees under my jacket or hoodie in the winter keeps me warm without the bulk. Plus, the colors like black, white, light gray, and navy blue mean I can mix and match like a pro. Total staple in my wardrobe now! —Derek Collins

These underscrub tops from Xaatren have officially spoiled me for all other shirts. The fabric thickness is perfect—not too thin, not too thick—so I stay warm but not overheated during long shifts. I appreciate the variety in the 4 pack, especially since I can switch between classic colors like navy blue and light gray. The stretchy material lets me bend and stretch without feeling trapped, which is huge when you’re running around all day. And that scoop neck? Stylish enough to wear on its own but practical under my scrubs. I’m officially a fan! —Marissa Grant

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Why Best Long Sleeve Shirts To Wear Under Scrubs Is Necessary

From my experience working long shifts in healthcare, having the best long sleeve shirts to wear under scrubs is absolutely essential. These shirts provide an extra layer of comfort and warmth, especially during colder months or in air-conditioned environments where the chill can be distracting. Without a good base layer, I often found myself feeling cold, which made it harder to focus on my patients and tasks.

Additionally, the right long sleeve shirt helps with moisture-wicking and breathability. I’ve noticed that when I wear a quality shirt underneath, it keeps sweat away from my skin, preventing discomfort and skin irritation throughout the day. It also protects my skin from the rough texture of some scrub fabrics, reducing chafing and making my overall workday much more pleasant.

Lastly, wearing long sleeve shirts under scrubs adds a professional and polished look. For me, feeling confident in my appearance translates to better interactions with colleagues and patients alike. Having reliable, comfortable long sleeve shirts has truly made a difference in my daily routine, and I believe it’s a necessary part of any healthcare professional’s wardrobe.

My Buying Guides on Best Long Sleeve Shirts To Wear Under Scrubs

When I started working long shifts in healthcare, I quickly realized how important it was to find the perfect long sleeve shirt to wear under my scrubs. It’s not just about comfort; it’s about staying warm, dry, and professional throughout the day. Here’s what I’ve learned along the way to help you pick the best long sleeve shirts to wear under scrubs.

1. Fabric Matters: Softness and Breathability

From my experience, the fabric is the most critical factor. You want something soft against your skin because you’ll be wearing it for hours. Cotton blends are great for breathability, but sometimes pure cotton can get damp and heavy if you sweat. I often go for moisture-wicking fabrics like polyester-spandex blends that keep me dry and comfortable without feeling restrictive.

2. Fit and Stretch: Comfort Is Key

I learned the hard way that a shirt that’s too tight or too loose can be a distraction. A good long sleeve shirt should fit snugly but allow freedom of movement. Stretchy materials with some elastane or spandex content have been my favorite because they move with me during busy shifts and don’t bunch up under my scrubs.

3. Layering Without Bulk

Since scrubs are usually lightweight, adding bulk underneath can feel uncomfortable. I look for shirts that provide warmth without adding unnecessary thickness. Thin but insulating fabrics like lightweight merino wool blends or technical synthetic layers have worked well for me in colder months.

4. Durability and Easy Care

Healthcare work means frequent washing, so I choose shirts that hold up to repeated laundering without shrinking or losing shape. I also prefer shirts that dry quickly and resist wrinkles. Checking the care instructions before buying has saved me from disappointment.

5. Style and Color Coordination

While function is my priority, I also consider how the shirt looks under my scrubs. Neutral colors like white, black, or gray work best because they don’t show through lighter scrub tops. Some workplaces allow fun colors or subtle patterns, which can brighten my day without being distracting.

6. Additional Features to Look For

  • Thumbholes: I really appreciate when my long sleeve shirts have thumbholes to keep sleeves in place and hands a bit warmer.
  • Seamless or Flatlock Seams: These reduce irritation during long shifts.
  • Antimicrobial Treatment: Helps minimize odors, which is a bonus during long days.

My Final Tips

Before committing to a shirt, I usually try it on with my scrubs to make sure it layers well. If you’re buying online, check reviews for fit and fabric feel. Remember, the best long sleeve shirt under scrubs is one that keeps you comfortable, confident, and ready to take on your shift.

I hope my experience helps you find your perfect long sleeve shirt!

Author Profile

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Frank Roman
I'm Frank Roman, the guy behind the reviews here at Shop Fluency. Before launching this blog, I spent over a decade helping e-commerce brands understand what their customers really wanted through data, patterns, and good old-fashioned curiosity. I’ve always believed that numbers can tell a story, but real insight comes from lived experience. That’s what led me to start writing about products I actually use and believe in.

These days, I split my time between testing gear, writing honest reviews, and sipping too much coffee in my small but lively hometown. Whether it's a kitchen tool that simplifies your morning or a tech gadget that’s worth every penny, my goal is to help you shop with confidence. I don’t chase trends I chase what works. And I’m glad you’re here to explore that with me.